Thincal capsules 120mg contain orlistat, a specific and reversible long-acting inhibitor of gastrointestinal lipase that is used to treat obesity and manage weight control in adults.  Dietary fat consists mainly of large triglycerides, which cannot be absorbed into the blood.  Triglycerides are hydrolysed (broken down) by an enzyme called gastrointestinal lipase in the stomach and small intestines.  The result is that smaller free fatty acids and monoglycerides can then be absorbed in the small intestine. 

Orlistat in Thincal capsules 120mg inhibits the action of the enzyme gastrointestinal lipase, which results in up to 30% undigested triglycerides passing through the gastrointestinal system without being absorbed.  This unabsorbed fat is excreted in the faeces.  This means that dietary fat cannot be used as a source of calories.  Therefore, less dietary fat is available to be used as energy by the body.  Instead, stores of body fat in adipose tissue will preferentially be used first, and fewer excess calories derived from fat in the diet will be stored as body fat. 

Unlike appetite suppressants, orlistat Thincal capsules 120mg is not absorbed into the blood.  Instead, it acts locally by binding to gastrointestinal lipase in your stomach and small intestines.  

Thincal capsules 120mg are fast-acting, and the effects can be seen within 24-48 hours, based on excreted fat content in the faeces.  If you stop taking Thincal, you will return to absorbing fat from the diet again, and this will reduce your weight loss.